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5 from 1 vote

Cajun Roast Beef

Best Cajun Roast Beef I have ever had in my life, you will never look at the deli version the same again.
Prep Time5 minutes
Cook Time1 hour
Marinate1 day
Total Time1 day 1 hour 5 minutes
Course: Main Course, Sandwich
Cuisine: American, Creole
Keyword: best cajun roast beef, cajun roast beef, cajun roast beef deli, cajun roast beef deli meat, creole beef recipe, creole recipe, Creole roast, easy cajun roast beef, homemade cajun roast, homemade cajun roast beef deli meat, Louisiana beef recipe
Servings: 12


  • 3 lbs round eye roast
  • 2 tbsp olive oil
  • 1 tbsp paprika
  • 2 tsp salt
  • 2 tsp garlic powder
  • 2 tsp onion powder
  • 1 tsp black pepper
  • 1 tsp dried oregano
  • 1 tsp dried thyme
  • 1 tsp celery seeds
  • ½ tsp ground cayenne pepper

Remoulade Sauce


    • In a small bowl: combine all the seasonings together.
    • Pat the roast dry with a paper towel. Pour and rub olive oil all over the roast. Then coat the roast with the seasoning mixture. Place the roast on a dish, cover and refrigerate for at least 12 hours or up to 24 hours (recommend for 24 hours for best result).
    • Remove the roast from the refrigerator and let sit at room temperature for 1 hour prior to cooking. Preheat the oven to 275°F.
    • Bake in the oven for 1 hour for medium-rare (internal temp.130°-135°F) (highly recommended) or 1 ½ hours for medium (internal temp. 140°-145°F). Open the door and confirm the anticipated Internal temperature using a meat thermometer.
    • Remove the roast from the oven and let cool (uncovered) to room temperature for 30 minutes. Transfer the roast to a dish. Cover and refrigerate for at least 4 hours or overnight (preferred). 
    • Use a meat slicer or a very sharp knife to thinly slice the meat just prior to eating. Toast bread. Spread remoulade sauce on the bread. Add roast, tomatoes, lettuce & onions.