Combine all the BBQ sauce ingredients together and mix well. Set aside. Optional: favorite store bought BBQ sauce can replace in this step.
Clean and pat the brisket dry with a paper towel. Trim and discard some of the fat.
Pour the beef broth in the instant pot.
In a small bowl: combine all the dry rub ingredients together and mix.
Rub the dry ingredients on both sides of the brisket.
Place the brisket in the cooker (IP).
Pour the BBQ sauce over the brisket.
Place the lid on. Pressure cook on high for 20 min per-pound and natural release for 20 minutes (exercise caution when releasing pressure from the cooker). Follow the manufacture instructions for how to do a quick release. Remove lid.
Transfer the brisket to a plate/cutting board. Cover with aluminum foil.
Press the sauté setting on high. Simmer the sauce for 15-20 minutes or until it thickens.
Slice the brisket.
Plate the brisket and cover with BBQ sauce.